Function and Biology

Solution structure of first SH3 domain of adaptor Nck

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00018
Domain description: SH3 domain
Occurring in:
  1. SH2/SH3 adapter protein NCK1
The deposited structure of PDB entry 2js2 contains 1 copy of Pfam domain PF00018 (SH3 domain) in Cytoplasmic protein NCK1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. SH2/SH3 adapter protein NCK1
IPR039801
Domain description: Epidermal growth factor receptor kinase substrate 8-like
Occurring in:
  1. SH2/SH3 adapter protein NCK1
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. SH2/SH3 adapter protein NCK1
IPR035562
Domain description: Nck1, SH3 domain 1
Occurring in:
  1. SH2/SH3 adapter protein NCK1

Structure domain

CATH CATH domain
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. SH2/SH3 adapter protein NCK1
The deposited structure of PDB entry 2js2 contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Cytoplasmic protein NCK1. Showing 1 copy in chain A.