2jn5 Summary

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Solution Structure of a Dodecapeptide from Alpha-Synuclein Bound with Synphilin-1

The structure was published by Xie, Y.Y., Zhou, C.J., Zhou, Z.R., et al., Song, A.X., Lin, D.H., and Hu, H.Y., in 2010 in a paper entitled "Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Alpha-synuclein. This molecule has the UniProt identifier P37840 (SYUA_HUMAN)search. The sample contained 12 residues which is < 90% of the natural sequence. Out of 12 residues 12 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Alpha-synuclein P37840 (1-12) (SYUA_HUMAN)search Homo sapienssearch 100% 12 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P37840 (1 - 12) Alpha-synuclein

Chain Sequence family (Pfam)
A (P37840) PF01387: Synucleinsearch