CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION
The structure was published by Yun, C.-H., Mengwasser, K.E., Toms, A.V., et al., Wong, K., Meyerson, M., and Eck, M.J., in 2008 in a paper entitled "The T790M Mutation in Egfr Kinase Causes Drug Resistance by Increasing the Affinity for ATP." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of EPIDERMAL GROWTH FACTOR RECEPTOR.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: