2j6f Summary

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N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) BOUND TO CBL-B PEPTIDE

The structure was published by Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., and Bravo, J., in 2006 in a paper entitled "Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely CD2-ASSOCIATED PROTEIN and E3 UBIQUITIN-PROTEIN LIGASE CBL-B.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CD2-ASSOCIATED PROTEIN Q9Y5K6 (1-62) (CD2AP_HUMAN)search Homo sapienssearch < 90% 62 93%
C E3 UBIQUITIN-PROTEIN LIGASE CBL-B Q13191 (902-912) (CBLB_HUMAN)search Homo sapienssearch < 90% 11 72%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q9Y5K6 (1 - 62) CD2-ASSOCIATED PROTEIN Homo sapiens
Q13191 (902 - 912) E3 UBIQUITIN-PROTEIN LIGASE CBL-B HOMO SAPIENS

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch Variant SH3 domainsearch
C
Chain InterPro annotation
A SH3 domainsearch CD2-associated proteinsearch
C