2izt Summary



A publication describing this structure is not available. The depositing authors are Bunkoczi, G.search; Salah, E.search; Rellos, P.search; Das, S.search; Fedorov, O.search; Savitsky, P.search; Debreczeni, J.E.search; Gileadi, O.search; Sundstrom, M.search; Edwards, A.search; Arrowsmith, C.search; Weigelt, J.search; Von Delft, F.search; Knapp, S.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of CASEIN KINASE I ISOFORM GAMMA-3. This molecule has the UniProt identifier Q9Y6M4 (KC1G3_HUMAN)search. The sample contained 330 residues which is < 90% of the natural sequence. Out of 330 residues 292 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CASEIN KINASE I ISOFORM GAMMA-3 Q9Y6M4 (35-362) (KC1G3_HUMAN)search Homo sapienssearch < 90% 330 89%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9Y6M4 (35 - 362) CASEIN KINASE I ISOFORM GAMMA-3 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch, Casein kinase 1 gamma C terminalsearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q9Y6M4) protein kinase activitysearch protein serine/threonine kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch ATP bindingsearch protein phosphorylationsearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch