CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN COMPLEXED WITH THE INHIBITOR ZD6474
The structure was published by Knowles, P.P., Murray-Rust, J., Kjaer, S., et al., Santoro, M., Ibanez, C.F., and Mcdonald, N.Q., in 2006 in a paper entitled "Structure and Chemical Inhibition of the Ret Tyrosine Kinase Domain." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2006.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: