Human estrogen receptor alpha ligand-binding domain in complex with compound 1D
The structure was published by Dykstra, K.D., Guo, L., Birzin, E.T., et al., Rohrer, S.P., Schaeffer, J.M., and Hammond, M.L., in 2007 in a paper entitled "Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Estrogen receptor.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: