Structure of the extracellular segment of human TRKA in complex with nerve growth factor
The structure was published by Wehrman, T., He, X., Raab, B., Dukipatti, A., Blau, H., and Garcia, K.C., in 2007 in a paper entitled "Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.4 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely High affinity nerve growth factor receptor and Beta-nerve growth factor.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: