› 2if7

X-ray diffraction
3Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-188441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SLAM family member 6 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 193 amino acids
Theoretical weight: 21.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96DU3 (Residues: 24-215; Coverage: 62%)
Gene names: KALI, SLAMF6, UNQ6123/PRO20080
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 121.196Å b: 148.452Å c: 86.572Å
α: 90° β: 112.86° γ: 90°
R-values:
R R work R free
0.216 0.213 0.266
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Follicular helper CD4 T cells (TFH).
Crotty S. (2011)
17 more

5 mentions without citation

Sequence, structure, function, immunity: structural genomics of costimulation.
Chattopadhyay et al. (2009)
4 more