› 2ie7

X-ray diffraction
1.75Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147018 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A5 Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 35.66 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P14668 (Residues: 2-319; Coverage: 100%)
Gene names: Anx5, Anxa5
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

3 bound ligands:
Ligand CA 7 x CA
Ligand SO4 4 x SO4
Ligand N2O 2 x N2O
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: R3
Unit cell:
a: 157.028Å b: 157.028Å c: 37.327Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.174 0.203

Quick links

Citations

9 review citations

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal.
Franks NP. (2008)
8 more

4 mentions without citation

Protein crystallography under xenon and nitrous oxide pressure: comparison with in vivo pharmacology studies and implications for the mechanism of inhaled anesthetic action.
Colloc'h et al. (2007)
3 more