spacer Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: HLA class II histocompatibility antigen, DR alpha chain

1 I K E E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L
61 A N I A V D K A N L E I M T K R S N Y T P I T N V P P E V T V L T N S P V E L R E P N V L I C F I D K F T P P V V N V T
121 W L R N G K P V T T G V S E T V F L P R E D H L F R K F H Y L P F L P S T E D V Y D C R V E H W G L D E P L L K H W E F
181 D A

Regions

CATH

2ianA01
4 .. 81
2ianA02
82 .. 181

SCOP

137163
13 .. 81
137162
83 .. 179

Chain B: HLA class II histocompatibility antigen, DRB1-1 beta chain

1 G D T R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y
61 W N S Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P K V T V Y P S K T Q P L Q H H N L L V C S V S
121 G F Y P G S I E V R W F R N G Q E E K A G V V S T G L I Q N G D W T F Q T L V M L E T V P R S G E V Y T C Q V E H P S V
181 T S P L T V E W R A

Regions

CATH

2ianB01
3 .. 92
2ianB02
93 .. 190

SCOP

137165
3 .. 92
137164
93 .. 190

Chain C: 15-mer peptide from Triosephosphate isomerase

1 G E L I G T L N A A K V P A D

Regions

Chain D: CD4+ T cell receptor E8 alpha chain

1 I Q V E Q S P P D L I L Q E G A N S T L R C N F S D S V N N L Q W F H Q N P W G Q L I N L F Y I P S G T K Q N G R L S A
61 T T V A T E R Y S L L Y I S S S Q T T D S G V Y F C A A L I Q G A Q K L V F G Q G T R L T I N P N I Q N P D P A V Y Q L
121 R D S K S S D K S V C L F T D F D S Q T N V S Q S K D S D V Y I T D K C V L D M R S M D F K S N S A V A W S N K S D F A
181 C A N A F N N S I I P E D T F F P S P E S S

Regions

CATH

2ianD01
1 .. 108

Chain E: CD4+ T cell receptor E8 beta chain

1 N A G V T Q T P K F R I L K I G Q S M T L Q C T Q D M N H N Y M Y W Y R Q D P G M G L K L I Y Y S V G A G I T D K G E V
61 P N G Y N V S R S T T E D F P L R L E L A A P S Q T S V Y F C A S T Y H G T G Y F G E G S W L T V V E D L N K V F P P E
121 V A V F E P S E A E I S H T Q K A T L V C L A T G F F P D H V E L S W W V N G K E V H S G V C T D P Q P L K E Q P A L N
181 D S R Y A L S S R L R V S A T F W Q N P R N H F R C Q V Q F Y G L S E N D E W T Q D R A K P V T Q I V S A E A W G R A D

Regions

CATH

2ianE01
3 .. 111
2ianE02
112 .. 237

Chain F: HLA class II histocompatibility antigen, DR alpha chain

1 I K E E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L
61 A N I A V D K A N L E I M T K R S N Y T P I T N V P P E V T V L T N S P V E L R E P N V L I C F I D K F T P P V V N V T
121 W L R N G K P V T T G V S E T V F L P R E D H L F R K F H Y L P F L P S T E D V Y D C R V E H W G L D E P L L K H W E F
181 D A

Regions

CATH

2ianF01
3 .. 81
2ianF02
82 .. 181

SCOP

137167
13 .. 81
137166
83 .. 179

Chain G: HLA class II histocompatibility antigen, DRB1-1 beta chain

1 G D T R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y
61 W N S Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P K V T V Y P S K T Q P L Q H H N L L V C S V S