Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor
The structure was published by Evdokimov, A.G., Pokross, M., Walter, R., et al., Gray, J., Maier, M., and Peters, K.G., in 2006 in a paper entitled "Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.15 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Receptor-type tyrosine-protein phosphatase beta. This molecule has the UniProt identifier P23467 (PTPRB_HUMAN). The sample contained 313 residues which is < 90% of the natural sequence. Out of 313 residues 279 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: