Abl kinase domain in complex with PD180970
The structure was published by Cowan-Jacob, S.W., Fendrich, G., Floersheimer, A., et al., Centeleghe, M., Fabbro, D., and Manley, P.W., in 2007 in a paper entitled "Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Proto-oncogene tyrosine-protein kinase ABL1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: