› 2hxo

X-ray diffraction
2.4Å resolution

Structure of the transcriptional regulator SCO7222, a TetR from Streptomyces coelicolor

Released:
DOI: 10.2210/pdb2hxo/pdb
PDB entry 2hxo coloured by chain, front view.
PDB entry 2hxo coloured by chain, side view.
PDB entry 2hxo coloured by chain, top view.
Source organism: Streptomyces coelicolor A3(2)
Entry authors: Singer AU, Skarina T, Zhang RG, Onopriyenko O, Edwards AM, Joachimiak A, Savchenko A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191754 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 237 amino acids
Theoretical weight: 25.25 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K463 (Residues: 1-236; Coverage: 100%)
Gene names: SC2H12.21c, SCO7222
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 54.088Å b: 97.479Å c: 100.971Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.226 0.26
Expression system: Escherichia coli

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