X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand
The structure was published by Benfield, A.P., Teresk, M.G., Plake, H.R., Delorbe, J.E., Millspaugh, L.E., and Martin, S.F., in 2006 in a paper entitled "Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Growth factor receptor-bound protein 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: