2hsa Summary


Crystal structure of 12-oxophytodienoate reductase 3 (OPR3) from tomato

The structure was published by Breithaupt, C., Kurzbauer, R., Lilie, H., et al., Huber, R., Macheroux, P., and Clausen, T., in 2006 in a paper entitled "Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of 12-oxophytodienoate reductase 3.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
B 12-oxophytodienoate reductase 3 Q9FEW9 (1-396) (OPR3_SOLLC)search Solanum lycopersicumsearch 100% 402 93%
A 12-oxophytodienoate reductase 3 Q9FEW9 (1-396) (OPR3_SOLLC)search Solanum lycopersicumsearch 100% 402 93%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9FEW9 (1 - 396) 12-oxophytodienoate reductase 3 Solanum lycopersicum

Chain Structural classification (CATH) Sequence family (Pfam)
B, A (Q9FEW9) Aldolase class Isearch PF00724: NADH:flavin oxidoreductase / NADH oxidase familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
B, A (Q9FEW9) response to jasmonic acidsearch oxidation-reduction processsearch signal transductionsearch fatty acid metabolic processsearch oxylipin biosynthetic processsearch response to ethylenesearch jasmonic acid mediated signaling pathwaysearch indoleacetic acid biosynthetic processsearch abscisic acid-activated signaling pathwaysearch response to woundingsearch tryptophan catabolic processsearch response to auxinsearch lipid metabolic processsearch jasmonic acid biosynthetic processsearch jasmonic acid metabolic processsearch response to water deprivationsearch hyperosmotic salinity responsesearch fatty acid biosynthetic processsearch FMN bindingsearch catalytic activitysearch oxidoreductase activitysearch 12-oxophytodienoate reductase activitysearch peroxisomesearch

Chain InterPro annotation
B, A NADH:flavin oxidoreductase/NADH oxidase, N-terminalsearch Aldolase-type TIM barrelsearch