Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Insulin receptor subunit beta (preferred)
PDBe Complex ID:
PDB-CPX-138939 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (7 distinct):
Insulin receptor subunit alpha
Molecule details ›
Chains: A, B
Length: 486 amino acids
Theoretical weight: 55.54 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 486 amino acids
Theoretical weight: 55.54 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P06213 (Residues: 28-512; Coverage: 36%)
Sequence domains:
Structure domains:
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 14-BM-D
Spacegroup:
P212121
Expression system: Cricetulus griseus
