2hoa Summary

pdbe.org/2hoa
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STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA

The structure was published by Guntert, P., Qian, Y.Q., Otting, G., Muller, M., Gehring, W., and Wuthrich, K., in 1991 in a paper entitled "Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1992.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of ANTENNAPEDIA PROTEIN. This molecule has the UniProt identifier Q7KSY7 (Q7KSY7_DROME)search. The sample contained 68 residues which is < 90% of the natural sequence. Out of 68 residues 68 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ANTENNAPEDIA PROTEIN Q7KSY7 (280-346) (Q7KSY7_DROME)search Drosophila melanogastersearch < 90% 68 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q7KSY7 (280 - 346) ANTENNAPEDIA PROTEIN Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (Q7KSY7) regulation of transcription, DNA-templatedsearch sequence-specific DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch transcription regulatory region sequence-specific DNA bindingsearch nucleussearch

Chain InterPro annotation
A Helix-turn-helix motifsearch Homeobox domainsearch Homeodomain-likesearch Homeobox, conserved sitesearch Homeodomain, metazoasearch