Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632
The structure was published by Yamaguchi, H., Miwa, Y., Kasa, M., et al., Amano, M., Kaibuchi, K., and Hakoshima, T., in 2006 in a paper entitled "Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Rho-associated protein kinase 2. This molecule has the UniProt identifier Q28021 (ROCK2_BOVIN). The sample contained 402 residues which is < 90% of the natural sequence. Out of 402 residues 383 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: