2h7h Summary


Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA

There is a Quite Interesting Protein Structure article for this entry.

A publication describing this structure is not available. The depositing authors are Rajan, S.S.search; Borovilos, M.search; Cuff, M.E.search; Kim, Y.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', and Viral jun transforming protein.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Viral jun transforming protein P05411 (210-271) (JUN_AVIS1)search Avian sarcoma virus 17search < 90% 62 93%
B Viral jun transforming protein P05411 (210-271) (JUN_AVIS1)search Avian sarcoma virus 17search < 90% 62 93%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05411 (210 - 271) Viral jun transforming protein Avian sarcoma virus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Leucine zipper domainsearch Single alpha-helices involved in coiled-coils or other helix-helix interfacessearch bZIP transcription factorsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P05411) sequence-specific DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch regulation of transcription, DNA-templatedsearch nucleussearch

Chain InterPro annotation
A, B Transcription factor Junsearch Basic-leucine zipper domainsearch Transcription factor, Skn-1-like, DNA-binding domainsearch Transcription Factor c-Jun/v-Junsearch