2h3o Summary


Structure of MERFT, a membrane protein with two trans-membrane helices

The structure was published by De Angelis, A.A., Howell, S.C., Nevzorov, A.A., and Opella, S.J., in 2006 in a paper entitled "Structure Determination of a Membrane Protein with Two Trans-membrane Helices in Aligned Phospholipid Bicelles by Solid-State NMR Spectroscopy." (abstract).

The structure was determined using Solid-state NMR and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of MerF. This molecule has the UniProt identifier Q56446 (Q56446_MORMO)search. The sample contained 61 residues which is < 90% of the natural sequence. Out of 61 residues 25 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MerF Q56446 (12-70) (Q56446_MORMO)search Morganella morganiisearch 100% 61 73%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q56446 (12 - 70) MerF Morganella morganii

Chain Structural classification (CATH) Sequence family (Pfam)
A bacterial mercury transporter, merfsearch Membrane transport protein MerFsearch
Chain InterPro annotation
A Mercury ion transport, MerFsearch