› 2gxq

X-ray diffraction
1.2Å resolution

HERA N-terminal domain in complex with AMP, crystal form 1

Released:
DOI: 10.2210/pdb2gxq/pdb
PDB entry 2gxq coloured by chain, front view.
PDB entry 2gxq coloured by chain, side view.
PDB entry 2gxq coloured by chain, top view.
Source organism: Thermus thermophilus HB27
Primary publication:
Crystal structure and nucleotide binding of the Thermus thermophilus RNA helicase Hera N-terminal domain.
Rudolph MG, Heissmann R, Wittmann JG, Klostermeier D
J Mol Biol 361 731-43 (2006)
PMID: 16890241

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126611 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat resistant RNA dependent ATPase Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 22.34 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
  • Canonical: O07897 (Residues: 1-207; Coverage: 41%)
Gene name: HERA
Sequence domains: DEAD/DEAH box helicase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand AMP 1 x AMP
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: C2
Unit cell:
a: 77.582Å b: 52.887Å c: 44.643Å
α: 90° β: 95.26° γ: 90°
R-values:
R R work R free
0.137 0.136 0.168
Expression system: Escherichia coli

Quick links

Citations

5 review citations

RNA helicase proteins as chaperones and remodelers.
Jarmoskaite et al. (2014)
4 more

1 mention without citation

DDX24 Mutations Associated With Malformations of Major Vessels to the Viscera.
Pang et al. (2019)