› 2gto

Solution NMR

Oxidized form of ADAP hSH3-N

Released:
DOI: 10.2210/pdb2gto/pdb
PDB entry 2gto coloured by chain, ensemble of 20 models, front view.
PDB entry 2gto coloured by chain, ensemble of 20 models, side view.
PDB entry 2gto coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Redox-regulated conformational changes in an SH3 domain.
Zimmermann J, Kühne R, Sylvester M, Freund C
Biochemistry 46 6971-7 (2007)
PMID: 17511475

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FYN-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 11.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15117 (Residues: 486-579; Coverage: 12%)
Gene names: FYB, FYB1, SLAP130
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Simulated Annealing with XPLOR NHI followed by water refinement
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures.
Ye et al. (2013)
1 more