Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-951717
The structure was published by Sabat, M., Vanrens, J.C., Clark, M.P., et al., Walter, R.L., Mekel, M.J., and Janusz, M.J., in 2006 in a paper entitled "The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Mitogen-activated protein kinase 14. This molecule has the UniProt identifier P47811 (MK14_MOUSE). The sample contained 348 residues which is 97% of the natural sequence. Out of 348 residues 336 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: