Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists
The structure was published by Kuhn, B., Hilpert, H., Benz, J., et al., Humm, R., Meyer, M., and Mohr, P., in 2006 in a paper entitled "Structure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Peroxisome proliferator-activated receptor gamma and Decamer from Nuclear receptor coactivator 1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: