Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate
The structure was published by Zhang, X., Gureasko, J., Shen, K., Cole, P.A., and Kuriyan, J., in 2006 in a paper entitled "An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Epidermal growth factor receptor and Peptide.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: