› 2gm3

X-ray diffraction
2.46Å resolution

Crystal Structure of an Universal Stress Protein Family Protein from Arabidopsis Thaliana At3g01520 with AMP Bound

Released:
DOI: 10.2210/pdb2gm3/pdb
PDB entry 2gm3 coloured by chain, front view.
PDB entry 2gm3 coloured by chain, side view.
PDB entry 2gm3 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Crystal structure of the protein At3g01520, a eukaryotic universal stress protein-like protein from Arabidopsis thaliana in complex with AMP.
Kim DJ, Bitto E, Bingman CA, Kim HJ, Han BW, Phillips GN
Proteins 83 1368-73 (2015)
PMID: 25921306

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185290 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Universal stress protein A-like protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 175 amino acids
Theoretical weight: 19.69 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8LGG8 (Residues: 2-175; Coverage: 99%)
Gene names: At3g01520, F4P13.7
Sequence domains: Universal stress protein family
Structure domains: HUPs

Ligands and Environments

1 bound ligand:
Ligand AMP 6 x AMP
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P1
Unit cell:
a: 63.351Å b: 65.662Å c: 73.014Å
α: 75.45° β: 75.04° γ: 66.11°
R-values:
R R work R free
0.221 0.218 0.261
Expression system: Escherichia coli

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Citations

2 review citations

PZQ Therapy: How Close are we in the Development of Effective Alternative Anti-schistosomal Drugs?
Aruleba et al. (2019)
1 more

5 mentions without citation

Universal Stress Proteins: From Gene to Function.
Luo et al. (2023)
4 more