2gli Summary

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FIVE-FINGER GLI/DNA COMPLEX

The structure was published by Pavletich, N.P. and Pabo, C.O., in 1993 in a paper entitled "Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 1993.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*TP*TP*TP*CP*GP*TP*CP*TP*TP*GP*GP*GP*TP*GP*GP*TP*CP*CP*AP*CP*G)-3'), DNA (5'-D(*AP*CP*GP*TP*GP*GP*AP*CP*CP*AP*CP*CP*CP*AP*AP*GP*AP*CP*GP*AP*A)-3'), and PROTEIN (FIVE-FINGER GLI).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (FIVE-FINGER GLI) P08151 (234-388) (GLI1_HUMAN)search Homo sapienssearch < 90% 155 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08151 (234 - 388) PROTEIN (FIVE-FINGER GLI) Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Classic zinc finger, C2H2search Classic Zinc Fingersearch Zinc finger, C2H2 typesearch, Zinc-finger double domainsearch

Chain ID Molecular function (GO)
A (P08151) nucleic acid bindingsearch metal ion bindingsearch

Chain InterPro annotation
A Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch