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PDBe Entry: 2gkl 
Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 1.86 Å, R-factor: 16.1%, Free R-factor: 19.617%, Spacegroup: C 2 2 21
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13/03/2007, deposition: 03/04/2006, last revision: 06/10/2009
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Garau, G.; Dideberg, O.
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Competitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila
ANTIMICROB.AGENTS CHEMOTHER. vol:51, pag:2136-2142 (2007) [PubMed ID 17307979 ]
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HYDROLASE, LACTAMASE, INHIBITOR, ZN
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3.5.2.6 ExPASy BRENDA (A)
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Aeromonas hydrophila 644(A)
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Beta-lactamase precursor (EC 3.5.2.6) P26918 (A)
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A
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1x8i, 1x8h, 1x8g
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| A |
Beta-lactamase |
Protein |
P26918 (BLAB_AERHY)
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227 |
99% |
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| A |
ZINC ION |
ZN
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| A |
PYRIDINE-2,4-DICARBOXYLIC ACID |
PD2
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| A |
GLYCEROL |
GOL
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