› 2gjf

Solution NMR

NMR structure of the computationally designed procarboxypeptidase-A (1AYE) domain

Released:
DOI: 10.2210/pdb2gjf/pdb
PDB entry 2gjf coloured by chain, ensemble of 20 models, front view.
PDB entry 2gjf coloured by chain, ensemble of 20 models, side view.
PDB entry 2gjf coloured by chain, ensemble of 20 models, top view.
Source organism: Unidentified
Primary publication:
High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design.
Dantas G, Corrent C, Reichow SL, Havranek JJ, Eletr ZM, Isern NG, Kuhlman B, Varani G, Merritt EA, Baker D
J Mol Biol 366 1209-21 (2007)
PMID: 17196978

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162715 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DESIGNED PROTEIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 78 amino acids
Theoretical weight: 9.01 KDa
Source organism: Unidentified
Expression system: Escherichia coli
Structure domains: Metallocarboxypeptidase-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Macromolecular modeling with rosetta.
Das et al. (2008)
8 more

3 mentions without citation

The stability and dynamics of computationally designed proteins.
Gonzalez et al. (2022)
2 more