Human estrogen receptor beta ligand-binding domain in complex with compound 45
The structure was published by Wilkening, R.R., Ratcliffe, R.W., Tynebor, E.C., et al., Hayes, E.C., Schaeffer, J.M., and Rohrer, S.P., in 2006 in a paper entitled "The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Estrogen receptor beta. This molecule has the UniProt identifier Q92731 (ESR2_HUMAN). The sample contained 241 residues which is < 90% of the natural sequence. Out of 241 residues 223 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: