Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Artemin and GDNF family receptor alpha-3 (preferred)
PDBe Complex ID:
PDB-CPX-130048 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Artemin
Molecule details ›
Chains: C, D
Length: 101 amino acids
Theoretical weight: 10.96 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 101 amino acids
Theoretical weight: 10.96 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q5T4W7 (Residues: 122-220; Coverage: 55%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
GDNF family receptor alpha-3
Molecule details ›
Chains: A, B
Length: 213 amino acids
Theoretical weight: 23.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: GDNF/GAS1 domain
Length: 213 amino acids
Theoretical weight: 23.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: O60609 (Residues: 151-363; Coverage: 58%)
Sequence domains: GDNF/GAS1 domain
Ligands and Environments
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.2.1
Spacegroup:
P21
Expression system: Trichoplusia ni
