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Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase

Solution NMR
PDB entry 2ge9 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ge9 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ge9 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tyrosine-protein kinase BTK
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-170299

Macromolecules

Tyrosine-protein kinase BTK
Chain: A
Length: 125 amino acids
Theoretical weight: 14.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06187 (Residues: 269-387; Coverage: 18%)
Gene names: AGMX1, ATK, BPK, BTK
Pfam: SH2 domain
InterPro:
CATH: SH2 domain
Tyrosine-protein kinase BTK in PDB entry 2ge9, assembly 1, front view.
Tyrosine-protein kinase BTK in PDB entry 2ge9, assembly 1, side view.
Tyrosine-protein kinase BTK in PDB entry 2ge9, assembly 1, top view.
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