2gda Summary

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REFINED SOLUTION STRUCTURE OF THE GLUCOCORTICOID RECEPTOR DNA-BINDING DOMAIN

The structure was published by Baumann, H., Paulsen, K., Kovacs, H., et al., Wright, A.P., Gustafsson, J.A., and Hard, T., in 1993 in a paper entitled "Refined solution structure of the glucocorticoid receptor DNA-binding domain." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1994.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of GLUCOCORTICOID RECEPTOR. This molecule has the UniProt identifier P06536 (GCR_RAT)search. The sample contained 72 residues which is < 90% of the natural sequence. Out of 72 residues 72 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A GLUCOCORTICOID RECEPTOR P06536 (439-510) (GCR_RAT)search Rattus norvegicussearch < 90% 72 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06536 (439 - 510) GLUCOCORTICOID RECEPTOR Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Nuclear receptorsearch Erythroid Transcription Factor GATA-1, subunit Asearch Zinc finger, C4 type (two domains)search

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P06536) zinc ion bindingsearch sequence-specific DNA binding transcription factor activitysearch sequence-specific DNA bindingsearch nucleussearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
A Zinc finger, nuclear hormone receptor-typesearch Zinc finger, NHR/GATA-typesearch