Structure of Thr 160 phosphorylated CDK2/cyclin A in complex with the inhibitor NU6271
The structure was published by Griffin, R.J., Henderson, A., Curtin, N.J., et al., Noble, M.E., Wang, L.Z., and Golding, B.T., in 2006 in a paper entitled "Searching for Cyclin-Dependent Kinase Inhibitors Using a New Variant of the Cope Elimination." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Cell division protein kinase 2 and Cyclin-A2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: