Assemblies
Assembly Name:
Tyrosine-protein kinase ABL1 and peptide
Multimeric state:
hetero dimer
Accessible surface area:
14041.84 Å2
Buried surface area:
1912.59 Å2
Dissociation area:
900.6
Å2
Dissociation energy (ΔGdiss):
8.11
kcal/mol
Dissociation entropy (TΔSdiss):
8.26
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132607
Assembly Name:
Tyrosine-protein kinase ABL1
Multimeric state:
monomeric
Accessible surface area:
14175.3 Å2
Buried surface area:
651.78 Å2
Dissociation area:
325.89
Å2
Dissociation energy (ΔGdiss):
1.09
kcal/mol
Dissociation entropy (TΔSdiss):
5.33
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132602
Macromolecules
Chains: A, B
Length: 287 amino acids
Theoretical weight: 33.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 287 amino acids
Theoretical weight: 33.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P00519 (Residues: 229-512; Coverage: 25%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
Chain: C
Length: 11 amino acids
Theoretical weight: 1.19 KDa
Source organism: Homo sapiens
Expression system: Not provided
Length: 11 amino acids
Theoretical weight: 1.19 KDa
Source organism: Homo sapiens
Expression system: Not provided
