2fyn Summary

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Crystal Structure Analysis of the double mutant Rhodobacter Sphaeroides bc1 complex

The structure was published by Esser, L., Gong, X., Yang, S., Yu, L., Yu, C.A., and Xia, D., in 2006 in a paper entitled "Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2006.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely Cytochrome b, Cytochrome c1, and Ubiquinol-cytochrome c reductase iron-sulfur subunit.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
D Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
G Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
J Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
M Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
P Cytochrome b Q02761 (1-445) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 445 96%
B Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
E Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
H Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
K Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
N Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
Q Cytochrome c1 Q02760 (23-285) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 269 95%
C Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%
F Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%
I Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%
L Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%
O Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%
R Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (1-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 187 95%


This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
Q02761 (1 - 445) Cytochrome b Rhodobacter sphaeroides
Q02760 (23 - 285) Cytochrome c1 Rhodobacter sphaeroides
Q02762 (1 - 187) Ubiquinol-cytochrome c reductase iron-sulfur subunit Rhodobacter sphaeroides

Chain Structural classification (CATH) Sequence family (Pfam)
A, D, G, J, M, P (Q02761) Cytochrome Bc1 Complex; Chain Csearch PF00032: Cytochrome b(C-terminal)/b6/petDsearch, PF13631: Cytochrome b(N-terminal)/b6/petBsearch
B, E, H, K, N, Q (Q02760) Cytochrome csearch, Single alpha-helices involved in coiled-coils or other helix-helix interfacessearch PF02167: Cytochrome C1 familysearch
C, F, I, L, O, R (Q02762) Single helix binsearch, 'Rieske'-like iron-sulphur domainssearch PF00355: Rieske [2Fe-2S] domainsearch, PF10399: Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signalsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, D, G, J, M, P (Q02761) respiratory chainsearch membranesearch integral component of membranesearch plasma membranesearch electron carrier activitysearch oxidoreductase activitysearch metal ion bindingsearch respiratory electron transport chainsearch oxidation-reduction processsearch
B, E, H, K, N, Q (Q02760) respiratory chainsearch plasma membranesearch membranesearch integral component of membranesearch electron carrier activitysearch heme bindingsearch iron ion bindingsearch metal ion bindingsearch oxidation-reduction processsearch
C, F, I, L, O, R (Q02762) integral component of membranesearch plasma membranesearch membranesearch ubiquinol-cytochrome-c reductase activitysearch oxidoreductase activity, acting on diphenols and related substances as donorssearch 2 iron, 2 sulfur cluster bindingsearch iron-sulfur cluster bindingsearch oxidoreductase activitysearch metal ion bindingsearch oxidation-reduction processsearch hydrogen ion transmembrane transportsearch

Chain InterPro annotation
A, D, G, J, M, P Cytochrome b/b6, N-terminalsearch Cytochrome b/b6, C-terminalsearch Di-haem cytochrome, transmembranesearch Cytochrome b/b6-like domainsearch
B, E, H, K, N, Q Cytochrome c1search Cytochrome c-like domainsearch
C, F, I, L, O, R Rieske iron-sulphur protein, C-terminalsearch Twin-arginine translocation pathway, signal sequencesearch Ubiquinol-cytochrome c reductase, iron-sulphur subunitsearch Rieske iron-sulphur proteinsearch Rieske [2Fe-2S] iron-sulphur domainsearch Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signalsearch Twin-arginine translocation pathway, signal sequence, bacterial/archaealsearch