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PDBe Entry: 2fya 
Crystal structure of the catalytic domain of the human beta1, 4-galactosyltransferase mutant M339H complex with manganese
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TRANSFERASE
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X-RAY DIFFRACTION
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Resolution: 1.9 Å, R-factor: 17.5%, Free R-factor: 22.6%, Spacegroup: C 2 2 21
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14/03/2006, deposition: 07/02/2006, last revision: 24/02/2009
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Ramakrishnan, B.; Ramasamy, V.; Qasba, P.K.
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Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.MOL.BIOL. vol:357, pag:1619-1633 (2006) [PubMed ID 16497331 ]
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M339H mutant, Mn binding, TRANSFERASE
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2.4.1.22 ExPASy BRENDA 2.4.1.38 ExPASy BRENDA 2.4.1.90 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)] [Contains: Processed beta-1,4-galactosyltransferase 1] P15291 (A)
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A
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2fy7, 2fyb, 2fyc, 2fyd
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| A |
Beta-1,4-galactosyltransferase 1 |
Protein |
P15291 (B4GT1_HUMAN)
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287 |
94% |
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| A |
MANGANESE (II) ION |
MN
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| A |
TRIETHYLENE GLYCOL |
PGE
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