spacer
EBI PDBe PDBeView

PDBe Entry: 2fxh view

Crystal structure of KatG at pH 6.5
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.9 Å, R-factor: 15.021%, Free R-factor: 17.732%, Spacegroup: P 21 21 21
Released 06/03/2007, deposition: 06/02/2006, last revision: 24/02/2009
Authors Carpena, X.search; Wiseman, B.search; Deemagarn, T.search; Herguedas, B.search; Ivancich, A.search; Singh, R.search; Loewen, P.C.search; Fita, I.search
Primary citation Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes.
BIOCHEMISTRYsearch vol:45, pag:5171-5179 (2006) [PubMed ID 16618106 ]search
Keywords catalase-peroxidasesearch, pH changessearch, isoniazidsearch, tuberculosissearch, OXIDOREDUCTASEsearch
EC 1.11.1.6 ExPASy BRENDA search 1.11.1.7 ExPASy BRENDA search (A B)
Organism Burkholderia pseudomallei 28450search(A B)
UniProt Peroxidase/catalase (EC 1.11.1.6),Catalase-peroxidase protein KatG (Catalase-peroxidase protein) Q939D2search (A B)
Solvent A, B
Related entries 1mwv, 2fxg, 2fxj
Polymers
Id Name Type UniProt Residues Observed
A, B catalase-peroxidase protein Protein Q939D2 (KATG_BURPS)search
 748 95%
Heterogens
Id Name Ligands
A, B SODIUM ION NA search
A, B PROTOPORPHYRIN IX CONTAINING FE HEM search
A, B 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL TRS search
B (4S)-2-METHYL-2,4-PENTANEDIOL MPD search
spacer