Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone
The structure was published by Wehenkel, A., Fernandez, P., Bellinzoni, M., et al., Labesse, G., Jackson, M., and Alzari, P.M., in 2006 in a paper entitled "The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.89 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Probable serine/threonine-protein kinase pknB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: