› 2fui

Solution NMR

NMR solution structure of PHD finger fragment of human BPTF in free state

Released:
DOI: 10.2210/pdb2fui/pdb
PDB entry 2fui coloured by chain, ensemble of 20 models, front view.
PDB entry 2fui coloured by chain, ensemble of 20 models, side view.
PDB entry 2fui coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Li H, Ilin S, Wang W, Duncan EM, Wysocka J, Allis CD, Patel DJ
Nature 442 91-5 (2006)
PMID: 16728978

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171405 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleosome-remodeling factor subunit BPTF Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12830 (Residues: 2865-2921; Coverage: 2%)
Gene names: BPTF, FAC1, FALZ
Sequence domains: PHD-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: The structure was solved using a simulated annealing by torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

149 review citations

The epigenomics of cancer.
Jones et al. (2007)
148 more

1 mention without citation

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Li et al. (2006)