mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
The structure was published by Diskin, R., Lebendiker, M., Engelberg, D., and Livnah, O., in 2007 in a paper entitled "Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2006.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of Mitogen-activated protein kinase 14. This molecule has the UniProt identifier Q16539 (MK14_HUMAN). The sample contained 367 residues which is 100% of the natural sequence. Out of 367 residues 331 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: