spacer Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen
CATH: Protein Structure Classification
CATH code 3.10.320.10 search
Domains
2fseA01 , 2fseC01
Name H-2 class ii histocompatibility antigen, e-k alpha chain. Chain: a, c.Engineered: yes. Other_details: chains a and c form a chimera with chains b and d, respectively. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, d. Engineered: yes. Other_details: chainsb and d form a chimera with chains a and c, respectively. Collagen alpha-1(ii). Chain: e, f. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: drosophila melanogaster.
Polymers A, C
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
2fseA02 , 2fseC02
Name H-2 class ii histocompatibility antigen, e-k alpha chain. Chain: a, c.Engineered: yes. Other_details: chains a and c form a chimera with chains b and d, respectively. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, d. Engineered: yes. Other_details: chainsb and d form a chimera with chains a and c, respectively. Collagen alpha-1(ii). Chain: e, f. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: drosophila melanogaster.
Polymers A, C
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 3.10.320.10 search
Domains
2fseB01 , 2fseD01
Name H-2 class ii histocompatibility antigen, e-k alpha chain. Chain: a, c.Engineered: yes. Other_details: chains a and c form a chimera with chains b and d, respectively. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, d. Engineered: yes. Other_details: chainsb and d form a chimera with chains a and c, respectively. Collagen alpha-1(ii). Chain: e, f. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: drosophila melanogaster.
Polymers B, D
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
2fseB02 , 2fseD02
Name H-2 class ii histocompatibility antigen, e-k alpha chain. Chain: a, c.Engineered: yes. Other_details: chains a and c form a chimera with chains b and d, respectively. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, d. Engineered: yes. Other_details: chainsb and d form a chimera with chains a and c, respectively. Collagen alpha-1(ii). Chain: e, f. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: drosophila melanogaster.
Polymers B, D
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
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