spacer Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: H-2 class II histocompatibility antigen, E-K alpha chain

1 E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L A N I
E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L A N I
29
61 A V D K A N L E I M T K R S N Y T P I T N V A P E V T V L S R S P V N L G E P N I L I C F I D K F S P P V V N V T W L R
A V D K A N L E I M T K R S N Y T P I T N V P P E V T V L T N S P V E L R E P N V L I C F I D K F T P P V V N V T W L R
121 N G R P V T E G V S E T V F L P R D D H L F R K F H Y L T F L P S T D D F Y D C E V D H W G L E E P L R K H W E F E
N G K P V T T G V S E T V F L P R E D H L F R K F H Y L P F L P S T E D V Y D C R V E H W G L D E P L L K H W E F
205

Regions

UniProt

P01903
29 .. 205 > 4 .. 180 (PDB)

Pfam

PF00993
4 .. 84 (PDB)
PF07654
93 .. 175 (PDB)

Chain B: HLA class II histocompatibility antigen, DRB1-1 beta chain

1 R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y W N S
R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y W N S
33
61 Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P T V T V Y P T K T Q P L Q H H N L L V C S V S D F Y
Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P K V T V Y P S K T Q P L Q H H N L L V C S V S G F Y
121 P G N I E V R W F R N G K E E E T G I V S T G L V R N G D W T F Q T L V M L E T V P Q S G E V Y T C Q V E H P S L T D P
P G S I E V R W F R N G Q E E K A G V V S T G L I Q N G D W T F Q T L V M L E T V P R S G E V Y T C Q V E H P S V T S P
181 V T V E W K A
L T V E W R A
219

Regions

UniProt

P04229
33 .. 219 > 4 .. 190 (PDB)

Pfam

PF00969
13 .. 87 (PDB)
PF07654
103 .. 185 (PDB)

Chain C: H-2 class II histocompatibility antigen, E-K alpha chain

1 E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L A N I
E H V I I Q A E F Y L N P D Q S G E F M F D F D G D E I F H V D M A K K E T V W R L E E F G R F A S F E A Q G A L A N I
29
61 A V D K A N L E I M T K R S N Y T P I T N V A P E V T V L S R S P V N L G E P N I L I C F I D K F S P P V V N V T W L R
A V D K A N L E I M T K R S N Y T P I T N V P P E V T V L T N S P V E L R E P N V L I C F I D K F T P P V V N V T W L R
121 N G R P V T E G V S E T V F L P R D D H L F R K F H Y L T F L P S T D D F Y D C E V D H W G L E E P L R K H W E F E
N G K P V T T G V S E T V F L P R E D H L F R K F H Y L P F L P S T E D V Y D C R V E H W G L D E P L L K H W E F
205

Regions

UniProt

P01903
29 .. 205 > 4 .. 180 (PDB)

Pfam

PF00993
4 .. 84 (PDB)
PF07654
93 .. 175 (PDB)

Chain D: HLA class II histocompatibility antigen, DRB1-1 beta chain

1 R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y W N S
R P R F L W Q L K F E C H F F N G T E R V R L L E R C I Y N Q E E S V R F D S D V G E Y R A V T E L G R P D A E Y W N S
33
61 Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P T V T V Y P T K T Q P L Q H H N L L V C S V S D F Y
Q K D L L E Q R R A A V D T Y C R H N Y G V G E S F T V Q R R V E P K V T V Y P S K T Q P L Q H H N L L V C S V S G F Y
121 P G N I E V R W F R N G K E E E T G I V S T G L V R N G D W T F Q T L V M L E T V P Q S G E V Y T C Q V E H P S L T D P
P G S I E V R W F R N G Q E E K A G V V S T G L I Q N G D W T F Q T L V M L E T V P R S G E V Y T C Q V E H P S V T S P
181 V T V E W K A
L T V E W R A
219

Regions

UniProt

P04229
33 .. 219 > 4 .. 190 (PDB)

Pfam

PF00969
13 .. 87 (PDB)
PF07654
103 .. 185 (PDB)

Chain E: Collagen alpha-1(II)

1 A G F K G E Q G P K G E P G
A G F K G E Q G P K G E P G
461 474

Regions

UniProt

P02458
461 .. 474 > 999 .. 1012 (PDB)

Pfam

PF01391
999 .. 1012 (PDB)

Chain F: Collagen alpha-1(II)

1 A G F K G E Q G P K G E P G
A G F K G E Q G P K G E P G
461 474

Regions

UniProt

P02458
461 .. 474 > 1999 .. 2012 (PDB)

Pfam

PF01391
1999 .. 2012 (PDB)
spacer