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EBI PDBe PDBeView

PDBe Entry: 2fpr view

Crystal structure the N-terminal domain of E. coli HisB. Apo Mg model.
Summary
Header HYDROLASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.7 Å, R-factor: 19.04%, Free R-factor: 21.979%, Spacegroup: C 2 2 21
Released 05/09/2006, deposition: 17/01/2006, last revision: 24/02/2009
Authors Rangarajan, E.S.search; Cygler, Msearch; Matte, A.search; Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)search
Primary citation Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.BIOL.CHEM.search vol:281, pag:37930-37941 (2006) [PubMed ID 16966333 ]search
Keywords Histidinola phosphate phosphatasesearch, HisBsearch, bifunctional enzyme.search, Structural Genomicssearch, Bacterial Structure Genomicssearch, Montreal-Kingston Bacterial Structural Genomics Initiativesearch, BSGIsearch, HYDROLASEsearch
EC 3.1.3.15 ExPASy BRENDA search 4.2.1.19 ExPASy BRENDA search (A B)
Organism Escherichia coli O157:H7 83334search(A B)
UniProt Histidine biosynthesis bifunctional protein hisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (IGPD)] Q9S5G5search (A B)
Solvent A, B
Related entries 2fps, 2fpu, 2fpw, 2fpx
Polymers
Id Name Type UniProt Residues Observed
A, B Histidine biosynthesis bifunctional protein hisB Protein Q9S5G5 (HIS7_ECO57)search
 176 90%
Heterogens
Id Name Ligands
B, A ZINC ION ZN search
A, B MAGNESIUM ION MG search
B SODIUM ION NA search
A, B BROMIDE ION BR search
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