spacer Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase
CATH: Protein Structure Classification
CATH code 2.30.30.40 search
Domains
2fo0A01
Name Proto-oncogene tyrosine-protein kinase abl1 (1b isoform). Chain: a. Fragment: abl n-cap (residues 1-531, residues 15-56 deleted). Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: c-abl. Expressed in:spodoptera frugiperda.
Polymers A
Hierarchy
Class Mainly Betasearch
Architecture Roll search
Topology SH3 type barrels. search
Homologous superfamily SH3 Domains search
 
CATH code 3.30.505.10 search
Domains
2fo0A02
Name Proto-oncogene tyrosine-protein kinase abl1 (1b isoform). Chain: a. Fragment: abl n-cap (residues 1-531, residues 15-56 deleted). Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: c-abl. Expressed in:spodoptera frugiperda.
Polymers A
Hierarchy
Class Alpha Betasearch
Architecture 2-Layer Sandwich search
Topology SHC Adaptor Protein search
Homologous superfamily SHC Adaptor Protein search
 
CATH code 3.30.200.20 search
Domains
2fo0A03
Name Proto-oncogene tyrosine-protein kinase abl1 (1b isoform). Chain: a. Fragment: abl n-cap (residues 1-531, residues 15-56 deleted). Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: c-abl. Expressed in:spodoptera frugiperda.
Polymers A
Hierarchy
Class Alpha Betasearch
Architecture 2-Layer Sandwich search
Topology Phosphorylase Kinase; domain 1 search
Homologous superfamily Phosphorylase Kinase; domain 1 search
 
CATH code 1.10.510.10 search
Domains
2fo0A04
Name Proto-oncogene tyrosine-protein kinase abl1 (1b isoform). Chain: a. Fragment: abl n-cap (residues 1-531, residues 15-56 deleted). Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: c-abl. Expressed in:spodoptera frugiperda.
Polymers A
Hierarchy
Class Mainly Alphasearch
Architecture Orthogonal Bundle search
Topology Transferase(Phosphotransferase); domain 1 search
Homologous superfamily Transferase(Phosphotransferase) domain 1 search
 
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