2fka Summary


Crystal structure of Mg(2+) and BeF(3)(-)-bound CheY in complex with CheZ(200-214) solved from a F432 crystal grown in CAPS (pH 10.5)

The structure was published by Guhaniyogi, J., Robinson, V.L., and Stock, A.M., in 2006 in a paper entitled "Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Chemotaxis protein cheY and C-terminal 15-mer from Chemotaxis protein cheZ.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Chemotaxis protein cheY P0A2D5 (1-129) (CHEY_SALTY)search Salmonella enterica subsp. enterica serovar Typhimurium str. LT2search 99% 129 99%
B C-terminal 15-mer from Chemotaxis protein cheZ P07800 (200-214) (CHEZ_SALTY)search Salmonella enterica subsp. enterica serovar Typhimurium str. LT2search < 90% 15 66%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P0A2D5 (1 - 129) Chemotaxis protein cheY Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
P07800 (200 - 214) C-terminal 15-mer from Chemotaxis protein cheZ

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0A2D5) CheY-relatedsearch Rossmann foldsearch PF00072: Response regulator receiver domainsearch
B Chemotaxis phosphatase, CheZsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P0A2D5) phosphorelay signal transduction systemsearch archaeal or bacterial-type flagellum-dependent cell motilitysearch chemotaxissearch cytoplasmsearch metal ion bindingsearch

Chain InterPro annotation
A Signal transduction response regulator, receiver domainsearch CheY-like superfamilysearch