2fh9 Summary


Structure and dimerization of the kinase domain from yeast Snf1

The structure was published by Nayak, V., Zhao, K., Wyce, A., et al., Lo, W.S., Berger, S.L., and Marmorstein, R., in 2006 in a paper entitled "Structure and Dimerization of the Kinase Domain from Yeast Snf1, a Member of the Snf1/AMPK Protein Family" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Snf1 kinase. This molecule has the UniProt identifier P06782 (SNF1_YEAST)search. The sample contained 274 residues which is < 90% of the natural sequence. Out of 274 residues 255 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Snf1 kinase P06782 (46-319) (SNF1_YEAST)search Saccharomyces cerevisiae S288csearch < 90% 274 93%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06782 (46 - 319) Snf1 kinase Saccharomyces cerevisiae

Chain Structural classification (CATH) Sequence family (Pfam)
A Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P06782) protein kinase activitysearch ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein serine/threonine kinase activitysearch protein phosphorylationsearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch