› 2ffx

X-ray diffraction
1.9Å resolution

Structure of Human Ferritin L. Chain

Released:
DOI: 10.2210/pdb2ffx/pdb
PDB entry 2ffx coloured by chain, front view.
PDB entry 2ffx coloured by chain, side view.
PDB entry 2ffx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human ferritin L chain.
Wang Z, Li C, Ellenburg M, Soistman E, Ruble J, Wright B, Ho JX, Carter DC
Acta Crystallogr D Biol Crystallogr 62 800-6 (2006)
PMID: 16790936

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin light chain Chain: J
Molecule details ›
Chain: J
Length: 173 amino acids
Theoretical weight: 19.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02792 (Residues: 2-174; Coverage: 99%)
Gene name: FTL
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

2 bound ligands:
Ligand CD 14 x CD
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: I432
Unit cell:
a: 151.601Å b: 151.601Å c: 151.601Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.241
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Ferritin family proteins and their use in bionanotechnology.
He et al. (2015)
3 more

17 mentions without citation

Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration.
Muhoberac et al. (2019)
16 more