2fek Summary

pdbe.org/2fek
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Structure of a protein tyrosine phosphatase

The structure was published by Lescop, E., Hu, Y., Xu, H., et al., Chen, J., Xia, B., and Jin, C., in 2006 in a paper entitled "The solution structure of Escherichia coli Wzb reveals a novel substrate recognition mechanism of prokaryotic low molecular weight protein-tyrosine phosphatases" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Low molecular weight protein-tyrosine-phosphatase wzb. This molecule has the UniProt identifier P0AAB2 (WZB_ECOLI)search. The sample contained 167 residues which is 100% of the natural sequence. Out of 167 residues 147 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Low molecular weight protein-tyrosine-phosphatase wzb P0AAB2 (1-147) (WZB_ECOLI)search Escherichia coli K-12search 100% 167 88%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0AAB2 (1 - 147) Low molecular weight protein-tyrosine-phosphatase wzb Escherichia coli K-12

Chain Sequence family (Pfam)
A (P0AAB2) PF01451: Low molecular weight phosphotyrosine protein phosphatasesearch

Chain ID Biological process (GO) Molecular function (GO)
A (P0AAB2) peptidyl-tyrosine dephosphorylationsearch protein dephosphorylationsearch polysaccharide biosynthetic processsearch colanic acid biosynthetic processsearch protein tyrosine phosphatase activitysearch hydrolase activitysearch phosphoprotein phosphatase activitysearch

Chain InterPro annotation
A Protein-tyrosine phosphatase/arsenate reductasesearch Protein-tyrosine phosphatase, low molecular weightsearch Phosphotyrosine protein phosphatase I superfamilysearch